JPS6345667B2 - - Google Patents
Info
- Publication number
- JPS6345667B2 JPS6345667B2 JP57135256A JP13525682A JPS6345667B2 JP S6345667 B2 JPS6345667 B2 JP S6345667B2 JP 57135256 A JP57135256 A JP 57135256A JP 13525682 A JP13525682 A JP 13525682A JP S6345667 B2 JPS6345667 B2 JP S6345667B2
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- general formula
- lower alkyl
- different
- ethylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813131146 DE3131146A1 (de) | 1981-08-06 | 1981-08-06 | Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3131146.6 | 1981-08-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5826871A JPS5826871A (ja) | 1983-02-17 |
JPS6345667B2 true JPS6345667B2 (en]) | 1988-09-12 |
Family
ID=6138726
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP57135256A Granted JPS5826871A (ja) | 1981-08-06 | 1982-08-04 | 新規ヘテロアリールオキシプロパノールアミンおよびその製法 |
Country Status (13)
Country | Link |
---|---|
US (1) | US4479962A (en]) |
EP (1) | EP0071950B1 (en]) |
JP (1) | JPS5826871A (en]) |
AT (1) | ATE16383T1 (en]) |
AU (1) | AU583247B2 (en]) |
CA (1) | CA1203236A (en]) |
DD (1) | DD202548A5 (en]) |
DE (2) | DE3131146A1 (en]) |
ES (1) | ES8304940A1 (en]) |
FI (1) | FI80024C (en]) |
HU (1) | HU189607B (en]) |
IL (1) | IL66439A0 (en]) |
ZA (1) | ZA825653B (en]) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3310891A1 (de) * | 1983-03-25 | 1984-09-27 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue indolinon-(2)-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte |
GB2163150B (en) * | 1984-07-19 | 1988-05-25 | Sandoz Ltd | 3-aminopropoxyaryl derivatives |
DE3428525A1 (de) * | 1984-08-02 | 1986-02-13 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von alkylendiamin-derivaten zur behandlung von durchblutungsstoerungen sowie arzneimittel, die diese verbindung enthalten |
DE3434271A1 (de) * | 1984-09-19 | 1986-03-20 | Beiersdorf Ag, 2000 Hamburg | Substituierte 3,4-dihydro-chinolin-2(1h)-one verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen |
DE3531658A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2815926A1 (de) * | 1978-04-13 | 1979-10-18 | Boehringer Mannheim Gmbh | Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
IE41248B1 (en) * | 1974-06-05 | 1979-11-21 | Ici Ltd | 1-(aryl-or hetero-aryl)oxy-3-(substituded-amino)propan-i-ol derivatives process for their manufacture and pharmaceutical compositions containing them |
DE2619164C2 (de) * | 1976-04-30 | 1985-07-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Indazolyl-(4)-oxy-propanolamine, Verfahren zu ihrer Herstellung und deren Verwendung |
LU77339A1 (en]) * | 1977-05-16 | 1979-01-19 | ||
DE2830211A1 (de) * | 1977-07-21 | 1979-02-01 | Sandoz Ag | Substituierte indol-derivate, ihre herstellung und verwendung |
DD146749A3 (de) * | 1977-12-01 | 1981-03-04 | Dieter Lehmann | Verfahren zur herstellung von phenoxyalkanolamin-derivaten |
DE2905877A1 (de) * | 1979-02-16 | 1980-08-28 | Boehringer Mannheim Gmbh | Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
EP0025111B1 (en) * | 1979-08-10 | 1984-07-25 | Sandoz Ag | 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them |
ZA804848B (en) * | 1979-08-10 | 1982-03-31 | Sandoz Ltd | 3-aminopropoxy deri-vatives, their preparation and pharmaceutical compositions containing them |
DE3023369A1 (de) * | 1980-06-23 | 1982-01-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Aryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1981
- 1981-08-06 DE DE19813131146 patent/DE3131146A1/de not_active Withdrawn
-
1982
- 1982-07-27 CA CA000408114A patent/CA1203236A/en not_active Expired
- 1982-08-02 IL IL66439A patent/IL66439A0/xx not_active IP Right Cessation
- 1982-08-02 ES ES514628A patent/ES8304940A1/es not_active Expired
- 1982-08-02 AU AU86681/82A patent/AU583247B2/en not_active Ceased
- 1982-08-02 US US06/403,968 patent/US4479962A/en not_active Expired - Fee Related
- 1982-08-03 DE DE8282106984T patent/DE3267291D1/de not_active Expired
- 1982-08-03 EP EP82106984A patent/EP0071950B1/de not_active Expired
- 1982-08-03 DD DD82242220A patent/DD202548A5/de unknown
- 1982-08-03 AT AT82106984T patent/ATE16383T1/de active
- 1982-08-03 FI FI822706A patent/FI80024C/fi not_active IP Right Cessation
- 1982-08-04 JP JP57135256A patent/JPS5826871A/ja active Granted
- 1982-08-05 HU HU822524A patent/HU189607B/hu not_active IP Right Cessation
- 1982-08-05 ZA ZA825653A patent/ZA825653B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0071950B1 (de) | 1985-11-06 |
AU8668182A (en) | 1983-02-10 |
CA1203236A (en) | 1986-04-15 |
AU583247B2 (en) | 1989-04-27 |
JPS5826871A (ja) | 1983-02-17 |
DE3131146A1 (de) | 1983-02-24 |
HU189607B (en) | 1986-07-28 |
FI822706A0 (fi) | 1982-08-03 |
IL66439A0 (en) | 1982-12-31 |
US4479962A (en) | 1984-10-30 |
ES514628A0 (es) | 1983-04-16 |
ZA825653B (en) | 1983-07-27 |
ES8304940A1 (es) | 1983-04-16 |
ATE16383T1 (de) | 1985-11-15 |
DD202548A5 (de) | 1983-09-21 |
EP0071950A1 (de) | 1983-02-16 |
FI80024B (fi) | 1989-12-29 |
DE3267291D1 (en) | 1985-12-12 |
FI80024C (fi) | 1990-04-10 |
FI822706L (fi) | 1983-02-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4234595A (en) | 3-Indolyl-tertiary butylaminopropanols | |
CA1134827A (en) | Heterocyclic oxypropanolamine derivatives | |
AU643316B2 (en) | (2-imidazolin-2-ylamino) quinoxaline derivatives and methods for using same | |
HU196593B (en) | Process for producing new decahydroquinoline derivatives and their salts and pharmaceutics comprising these derivatives | |
US4314943A (en) | Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols | |
EP0014928A1 (de) | Neue Piperidinopropylderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel | |
US4367235A (en) | 2-Benzimidazolinone compounds and therapeutic compositions | |
JPS5967270A (ja) | イソキノリン誘導体の製法 | |
US4143149A (en) | Indazolyl-(4)-oxypropanolamine compounds and therapeutic compositions | |
JPS6345667B2 (en]) | ||
JP2512314B2 (ja) | 新規のインダン誘導体、その製造方法及び薬剤としてのその使用 | |
JPS59144763A (ja) | 1−〔1−ベンズイミダゾリル〕−n−〔2−(4−ヒドロキシ−3−メトキシフエニル)−2−ヒドロキシエチル〕−3−アミノブタン化合物、該化合物を含有する医薬、及び該化合物の製 | |
PL182361B1 (pl) | Pochodne 6-metoksy-1H-benzotriazolo-5-karboksyamidu, sposoby ich wytwarzaniai kompozycje farmaceutyczne zawierajace te pochodne PL PL PL PL PL PL PL PL | |
EP0029992B1 (de) | Neue Aminopropanolderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel | |
US4215134A (en) | 4-Hydroxy-2-benzimidazoline-thione compounds and pharmaceutical compositions containing them | |
JPS624263A (ja) | ヒドロキシアルコキシ―4―フェニルプロピルインドールの新規な誘導体及びその塩、それらの製造方法並びに不整脈防止剤 | |
HU183555B (en) | Process for preparing n-/1-allyl-2-pyrrolidinyl-methyl/-2-methoxy-4-amino-5-methyl-sulphamoyl-benzamide | |
JP3857313B2 (ja) | 3(2h)−ピリダジノン誘導体及びその化合物含有の製薬学的組成物 | |
US4495352A (en) | Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols | |
JPS6024100B2 (ja) | アミノプロパノ−ル−誘導体の製法 | |
JPS6061569A (ja) | 新規な3位置換アミン誘導体 | |
US4105768A (en) | Hypotensive substituted 1,2,4-triazoles | |
JPS63216865A (ja) | 鎮痛薬として有用な1−[(4−モルホリニル)アルキル]−1h−インドールおよびその製造方法 | |
US3989836A (en) | Method for treating cardiovascular circulatory insufficiencies and hypotonia with 2-hydroxyphenyl-1-oxa-4-azaspiroalkane derivatives | |
JPS5959675A (ja) | 置換ベンゾトリアゼピン化合物 |